KaramMD Trifecta

The Complete Anti-Aging Routine

4.7
Rated 4.7 out of 5 stars
1,256 Reviews

A simple skincare system proven to give you healthier, younger-looking skin in 3 easy steps—formulated with powerful active ingredients to target all aspects of aging skin simultaneously.

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MD Formulated

Clinically Proven

Premium Ingredients

For All Skin Types

Cruelty Free

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Clinically Proven to Fight Aging Skin

The Trifecta system visibly reduces signs of aging in as little as 4 weeks when used consistently. We adhere to the highest product standards and validate efficacy through rigorous third-party testing. After 8 weeks of usage, the clinical study proved:

100% of subjects had improvement in skin’s moisture.

100% of subjects had improvement in fine lines & wrinkles.

91% of subjects had improvement in skin’s firmness.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Truly Innovative
Anti-Aging Formulas

1. POWERFUL YET GENTLE
Meticulously crafted to ensure the right combination of anti-aging ingredients, gentle enough for even the most sensitive skin.


2. COMPREHENSIVE RESULTS, SIMPLIFIED
Our formulations consolidate up to 10 products into a 3-step routine, fundamentally addressing all aspects of aging simultaneously.


3. TARGETED ANTI-AGING ESSENTIALS
Premium ingredients and potent actives scientifically proven to prevent or reverse signs of aging and targeted to make changes on the cellular level.

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

Great Skin Made Simple

The Trifecta was developed by world renowned skin and facial rejuvenation expert Dr. Amir Karam. This routine is formulated with only the best high-quality ingredients, and designed to deliver results that only get better over time. Learn more about the creation of the Trifecta. 

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

How to Use

Rinse: Apply to wet skin, massage in circular motions, then rinse clean.

Quench: Apply 2 pumps to slightly damp face, eye area, and neck.

Illuminate: Apply 3 pumps to face, eye area, and neck.

Repeat this routine morning and night--do not skip applications. Consistent use for a minimum of 3-6 months for visible, lasting change.

HOW TO USE: TRIFECTA ROUTINE

Read the KaramMD Journal

Skincare Advice You Can Trust

The Best Anti-Aging Ingredients

The Best Anti-Aging Ingredients

When assessing your skincare products, it is essential they include the following anti-aging ingredients. Each of these ingredients play a unique role in skin health and are crucial to achieving y...

Dr. Karam's Philosophy for an Effective Skincare Routine

Dr. Karam's Philosophy for an Effective Skincare Routine

I believe I’ve finally found the secret to anti-aging. After 20 years of experience—and a lot of patience (and patients) throughout my career—I came to understand that skincare is more than just t...

KaramMD Trifecta skincare routine: Rinse Daily Cleanser, Quench Vitamin C Serum, and Illuminate Anti-Aging Cream held in a single hand.

Trifecta 101: What You Need to Know When Starting Your New Skincare Routine

Whether you’re completely new to skincare or transitioning to the Trifecta system, this guide will walk you through what to expect as you begin your skincare journey.

INGREDIENTS

Aloe Barbadensis (Aloe Vera) Leaf Juice*, Aqua/Water/Eau, Lauryl Glucoside, Glycerin, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Sodium Cocoyl Apple Amino Acids, Brassica Oleracea Italica (Broccoli) Seed Oil, Epilobium Angustifolium (Fireweed) Flower/Leaf/Stem Extract, Cocamidopropyl Dimethylamine, Arnica Montana (Mountain Arnica) Flower Extract, Phenoxyethanol, Sodium Chloride, Caprylyl Glycol, Hexylene Glycol, Sodium Hydroxide, Ethylhexylglycerin, Sodium Phytate, Glycolic Acid, Dimethylaminopropylamine, Dichloroacetic Acid, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Metabisulfite, Fragrance/Parfum, Limonene, Geraniol, Hexyl Cinnamal, Linalool.

*Organic Ingredient

Frequently Asked Questions

Our caring team of experts has the answers.

4.7
Rated 4.7 out of 5 stars
Based on 1,256 reviews
1,256 reviews
  • JA
    Julie A.
    Verified Buyer
    23 hours ago
    Rated 4 out of 5 stars
    Skin refreshed

    I've been using Trifecta for couple of months and have been receiving monthly facials for over 15 years. My skin concerns are surrounding aging skin, dark spots, wrinkles and dryness. I can state my skin feels softer and more hydrated after utilizing Enrich. I've noticed my skin appears to be evening out with the texture. I suffer from dry skin as well as having sensitivity to products containing vitamin c, which did cause me to contemplate my purchase of Trifecta. I have experienced rash episodes since utilizing trifecta and I believe it's due to the vitamin c. I really want this product to work so I've cut back to once a day with the routine. Kinda on the fence as to whether to continue.

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    17 hours ago

    Thank you for sharing your thoughtful feedback, Julie! We're pleased to hear about the positive changes you've noticed in your skin's texture and hydration levels, particularly with Enrich. Your extensive experience with professional skincare through regular facials makes your observations especially valuable.

    We understand your concerns regarding Vitamin C sensitivity, and we appreciate you being proactive in adjusting your routine to once daily to better suit your skin's needs. The skin's response to active ingredients can vary, and it's important to listen to what your skin is telling you. While our Trifecta formula is carefully balanced to be gentle and effective, we recognize that everyone's skin is unique.

    The improvements you've noticed in softness, hydration, and texture alignment are encouraging signs that aspects of the formula are working well for your skin. These benefits are key targets in our formulation, especially for addressing aging concerns and dryness.

    Given your skin's sensitivity, we understand your hesitation about continuing use. Your modified approach of once-daily application shows a thoughtful understanding of your skin's needs. While our formula is designed to work synergistically with optimal results from twice-daily use, adapting the frequency to better suit your skin's tolerance is a sensible approach. If you would like personalized tips please reach out to our customer care team and they would be happy to assist you.

    We're honored to be part of your sophisticated skincare journey, especially given your long-term commitment to professional skincare. Your experience and feedback are invaluable to us as we continue to support our community in achieving their best skin yet.

  • C
    Christine
    Yesterday
    Rated 5 out of 5 stars
    5 Stars

    Excellent products. Easy to use and effective. People have commented on my skin.

  • JP
    Jennifer P.
    Verified Buyer
    2 days ago
    Rated 5 out of 5 stars
    Incredible moisture!

    I just completed my first month using trifecta and I’m definitely noticing so much more moisture in my skin. It feels so much more healthy and plump. I’m looking forward to the ongoing benefits! I also enjoy the email updates. I get along with the easy monthly subscription delivery. I completely trust Dr Karam and his products and highly recommend !

    KS Profile picture for KaramMD Skin
    KaramMD Skin
    17 hours ago

    Thank you for your wonderful review, Jennifer P.! We're absolutely thrilled to hear about your first month's experience with the Trifecta system. It's particularly touching to hear how you've noticed such significant improvements in your skin's moisture levels and overall health—these are exactly the kind of transformative results we aim for with our formulations. We love that you're enjoying the plumpness and hydration that Trifecta provides, and we're excited for you to experience even more benefits as you continue your skincare journey. Your appreciation of our email updates and subscription service truly validates our commitment to creating a seamless experience for our customers. Your trust in Dr. Karam and our science-backed approach means the world to us, and we're deeply grateful to have you as part of the KaramMD Skin community. Thank you for sharing your inspiring experience with us!

  • C
    Carol
    1 week ago
    Rated 5 out of 5 stars
    5 Stars

    Karam MD Trifecta after just using 2 days morning and night, my skin already feels softer, looks brighter and better. I love the product also because it’s easy and is gentle. I just wish it was more affordable for my income.

    CB